Pre-proposal Deadline:  December 4, 2015 (Optional)

Full Application Deadline:  February 19, 2016


PURPOSE:  The Arizona Alzheimer’s Disease Core Center (ADCC) invites applications for pilot studies to support research in the fields of Alzheimer’s disease, related disorders or aging.


ELIGIBILITY REQUIREMENTS:  Applications are solicited from young investigators or established investigators proposing a new line of research in this field.  Applicants must be:

  • 5 years or less from postdoctoral or residency training, or
  • from another field and applying his/her expertise to the area for the first time, or
  • proposing to test the feasibility of a new research project

Investigators who have received a previous award are not automatically eliminated from applying for a second pilot grant as long as the application meets the above criteria.


MECHANISMS OF SUPPORT:  Two grants of up to $30,000 direct costs (plus applicable indirect costs)will be made, contingent on approval of the Arizona Alzheimer’s Disease Core Center competitive renewal grant proposal. The funding period is for one year (July 1, 2016 – June 30, 2017).  Additional awards may be made through Arizona Alzheimer’s Consortium state funds, if available.


RESEARCH OBJECTIVES:  The Arizona Alzheimer’s Disease Core Center Pilot Study program is designed to facilitate new research in the fields of Alzheimer’s disease, related disorders and aging.  Information obtained should allow subsequent submission of competitive grant support through the National Institutes of Health, or other extramural funding agencies.  Proposals that utilize data available through the National Alzheimer’s Coordinating Center (Minimum Data Set, Uniform Data Set, Neuropathology Data Set, etc. – see; that are related to the disciplines of the ADCC Cores/Components (Clinical, Data Management and Statistics, Neuropathology, Outreach and Recruitment, Research Education – see; or that promote the study of Hispanic or Native Americans are encouraged, but not required.  All proposals must include a preliminary plan and timeline for submission of a competitive grant application.



Optional Pre-proposal:  If applicants desire prior evaluation on their proposed application, a pre-proposal (not to exceed five pages following the format of the “Research Plan” on the following page) maybe sent by December 4, 2015 to Carol A. Barnes, Ph.D. via email attachment care of Michelle Carroll  While pre-proposals are not required, it would permit applicants to receiveinitial feedback and suggestions that might help strengthen the full proposal.   Please send in Word or PDF format.  Pre-Proposals will be sent to external reviewers for rapid feedback.  Constructive recommendations will be available to applicants by early January 2016.


Full Application:  The PHS research grant application fillable forms must be used in applying for these funds (available at  All components of the proposal, including appendices, should be sent to Dr. Carol Barnes by email attachment in a single file in PDF format c/o Michelle Carroll at in PDF format.


Applications must include:

  • Face page (form page 1)
  • Summary, Relevance, Project/Performance Sites, Senior/Key Personnel, etc. (form page 2)
  • Detailed Budget (form page 4) – Budget limited to $30,000 direct costs plus applicable indirect costs
  • Budget Justification
  • Biographical Sketch(es) for Key Personnel following new format:

  • Resources
  • Research Plan – limited to 5 pages and should include:
  1. Specific Aims
  2. Research Strategy (Significance, Innovation, Approach)
  3. Timeline and Plan for Submission of Competitive Grant Application
  • Bibliography and References Cited
  • Protection of Human Subjects (if applicable)
  • Vertebrate Animals (if applicable)
  • Checklist (including your institutional indirect cost calculation)
  • A cover letter with the names and contact information for 3-4 potential qualified reviewers.

Appendices are limited to three publications, manuscripts, abstracts, patents or other printed materials directly relevant to the proposal.


Applicants may also wish to identify a mentor, collaborator or consultant to advise or assist them on the project.  Potential mentors, collaborators, consultants should be listed in the grant cover letter.  Applicants who would like suggestions for appropriate matches should speak to Dr. Eric Reiman (Director, Arizona Alzheimer’s Consortium), or Dr. Carol Barnes (Director, Ad Hoc Review Program).  Contact information is listed below.


APPLICATION REVIEW CRITERIA:  Applications will be reviewed for scientific and technical merit by two relevant outside experts, and by a member of the ADCC’s Biostatistics Working Group. Applications will be rated based on 1) significance, 2) quality, innovation and feasibility, 3) use of NACC and/or Core facilities, 4) potential of applicant to develop a successful research program in the field, 5) likelihood of leading to a successful grant application, and 6) for sound experimental design and statistical approach.  If the grant was reviewed previously, the applicant may include a summary of the substantive changes made to the proposal in their cover letter.  Final award decisions will be made by the Executive Committee of the ADCC in ~ May 2016.  Notification of awards will be available in June 2016.  The anticipated funding start date of successful applications is July 1, 2016.


INQUIRIES:  Inquiries are encouraged.  Inquiries regarding ADCC core resources or expertise related to the applicant’s field of interest can be directed to:

Eric M. Reiman, M.D., Director, Arizona Alzheimer’s Consortium

Phone: (602) 839-6999



Inquiries regarding application and review procedures can be directed to:

Carol A. Barnes, Ph.D., Director, Ad Hoc Review Program

Phone: (520) 626-2096



Inquiries regarding statistical approach can be directed to:

Kewei Chen, Ph.D., Data Management & Statistics Co-Leader/Biostatistics Program Director

Phone: (602) 839-4851